Edexcel GCSE Combined Science
Edexcel GCSE Combined Science revision for Edexcel Combined Science (1SC0): 14 topics and 321 short lessons, each with R.E.C.I.P.E. recall steps and a quiz. The topics follow the Edexcel specification.
1. Key concepts in biology
- Core practical: Microscopes, magnification and scientific drawings
- Core practical: The effect of pH on enzyme activity
- Core practical: Osmosis in potatoes
- Sub-cellular structures in animal, plant and bacterial cells
- Specialised cells: sperm, egg and ciliated epithelial cells
- How microscope technology has changed our view of cells
- Number, size and scale, and estimation
- Units for cells: milli, micro, nano and pico
- How enzymes work: the active site and specificity
- Denaturing of enzymes
- Effects of temperature, substrate concentration and pH
- Rate calculations for enzyme activity
- Enzymes as biological catalysts in synthesis and breakdown
- Transport into and out of cells: diffusion, osmosis and active transport
- Calculating percentage gain and loss of mass in osmosis
- How Mendeleev arranged the elements in his periodic table
- How Mendeleev used his table to predict undiscovered elements
- Metals and non-metals in the periodic table and their atomic structure
- Electronic configurations of the first 20 elements
- Electronic configuration and position in the periodic table
- Ionic bonding and dot and cross diagrams
- Ions
- Protons, neutrons and electrons in simple ions
- Formation of ions in ionic compounds
- The endings -ide and -ate in compound names
- Formulae of ionic compounds
- Ionic lattice structure
- Formation of a covalent bond
- Covalent bonding and molecules
- Size of atoms and small molecules
- Dot and cross diagrams of simple molecules
- Types of substance and their properties
- Properties of ionic compounds
- Properties of simple molecular substances
- Graphite and diamond
- Structures of graphite and diamond
- Uses of graphite and diamond
- Properties of fullerenes and graphene
- Poly(ethene) and simple polymers
- Properties of metals
- Limitations of models and representations
- Properties of metals and non-metals
- Relative formula mass and percentage by mass
- Empirical formulae from masses
- Empirical and molecular formulae
- Finding the empirical formula of magnesium oxide
- The law of conservation of mass
- Calculating reacting masses
- Concentration of solutions in g/dm3
- The mole and the Avogadro constant
- Calculations with moles and particles
- Limiting reactants and the mass of product
- Deducing stoichiometry from masses
2. Cells and control
- Mitosis and the cell cycle
- Why mitosis is important
- Mitosis makes identical diploid cells
- Cancer and uncontrolled cell division
- Growth in animals and plants
- The importance of cell differentiation
- Percentile charts and growth
- Stem cells and meristems
- Stem cells in medicine: benefits and risks
- Neurones, receptors and synapses
- The reflex arc
- Interpreting paper chromatograms
- Core practical: inks, chromatography and simple distillation
- Making water potable
- Newton's second law
- Weight, mass and W = m × g
- Measuring weight
- Weight and gravitational field strength
- Core practical: force, mass and acceleration
- Circular orbits and changing velocity
- Centripetal force
- Inertial mass
- Newton's third law
- Momentum
- Examples of momentum in collisions
- Force as change in momentum over time
- Measuring human reaction times
- Stopping distance
- Factors affecting stopping distance
- Factors affecting a driver's reaction time
- Dangers of large decelerations and estimating forces on the road
3. Genetics
- Meiosis and gametes
- The structure of DNA
- Genome and genes
- Extracting DNA from fruit
- Alleles and differences in inherited characteristics
- Genetics key terms
- Monohybrid inheritance, Punnett squares and pedigrees
- How the sex of offspring is determined
- Calculating outcomes from crosses and pedigrees
- Multiple genes and phenotype
- Causes of genetic variation
- The Human Genome Project
- Genetic variation and mutations
- Effects of mutations on the phenotype
- Acids and alkalis as sources of ions
- The pH scale
- Dilute and concentrated solutions
- Strong and weak acids
- Bases and the reactions of bases with acids
- Alkalis as soluble bases
- Reactions of acids with metals, oxides, hydroxides and carbonates
- Core practical: Preparing pure, dry hydrated copper sulfate crystals
- Acid-alkali titration to prepare a pure, dry salt
- Movement of ions during electrolysis
- Electrolysis of copper chloride and sodium chloride solutions
- Electrolysis of molten binary ionic compounds
- Half equations at the electrodes
- Oxidation and reduction as loss or gain of electrons
- Reduction at the cathode and oxidation at the anode
- Electrolysis of copper sulfate with copper electrodes and purifying copper
- Core Practical: Electrolysis of copper sulfate solution
4. Natural selection and genetic modification
- Charles Darwin's theory of evolution by natural selection
- Resistant organisms and antibiotic resistance
- Evidence for human evolution from fossils
- Evidence for human evolution from stone tools
- Three domains and five kingdoms
- Selective breeding
- Describe genetic engineering as a process which involves modifying the genome of an organism to introduce desirable characteristics
- Describe the main stages of genetic engineering including the use of: a restriction enzymes b ligase c sticky ends d vectors
- Evaluate the benefits and risks of genetic engineering and selective breeding in modern agriculture and medicine, including practical and ethical implications
- Deduce the relative reactivity of some metals, by their reactions with water, acids and salt solutions
- Recall that the extraction of metals involves reduction of ores
- Explain how a metal’s relative resistance to oxidation is related to its position in the reactivity series
- Evaluating data from a life cycle assessment
- Reversible reactions
- Making ammonia and dynamic equilibrium
- Conditions for the Haber process
- Predicting changes in the position of equilibrium
5. Health, disease and the development of medicines
- Health as complete well-being
- Communicable and non-communicable diseases
- Why one disease raises the risk of others
- Pathogens
- Common infections
- How pathogens spread and how to stop them
- Sexually transmitted infections: chlamydia and HIV
- Physical barriers and chemical defences
- The specific immune system and antibodies
- Immunisation with an inactive pathogen
- Antibiotics and bacterial infections
- Developing new medicines
- Non-communicable diseases and their causes
- Lifestyle factors and non-communicable disease
- Treatments for cardiovascular disease
- Electromagnetic waves are transverse and travel at the same speed in a vacuum
- Core Practical: Refraction in a rectangular glass block
- Groupings of the electromagnetic spectrum
- The electromagnetic spectrum
- Harmful effects of electromagnetic radiation
- Uses of electromagnetic radiation
6. Plant structures and their functions
- Photosynthetic organisms as producers
- The photosynthesis reaction
- Limiting factors of photosynthesis
- Interactions between limiting factors
- Core practical: light intensity and photosynthesis
- Light intensity, distance and the inverse square law
- Root hair cells: adaptations for absorption
- Xylem and phloem: structure and function
- Transpiration and the stomata
- Translocation of sucrose
- Environmental factors and water uptake
- Calculating the rate of transpiration
- Displacement reactions of the halogens
- Why the noble gases are inert
- Uses of the noble gases
- Patterns in the noble gases
- How the atomic model has changed
- Beta-minus decay
- Beta plus decay
- Effects of radioactive decay on nuclei
- Gamma radiation and nuclear rearrangement
- Balancing nuclear equations
- How the activity of a source decreases
- The becquerel as the unit of activity
- Half-life
- Random decay and predicting half-life
- Half-life calculations and graphs
- Dangers of ionising radiation
- Safety precautions and medical exposure
- Contamination and irradiation
7. Animal coordination, control and homeostasis
- Hormones, endocrine glands and target organs
- Adrenalin and the fight or flight response
- Thyroxine and negative feedback
- The menstrual cycle
- Hormones in the control of the menstrual cycle
- Hormonal contraception
- Evaluate hormonal and barrier methods of contraception
- Explain the use of hormones in Assisted Reproductive Technology (ART) including IVF and clomifene therapy
- Explain the importance of maintaining a constant internal environment in response to internal and external change
- Explain how the hormone insulin controls blood glucose concentration
- Explain how blood glucose concentration is regulated by glucagon
- Explain the cause of type 1 diabetes and how it is controlled
- Type 2 diabetes: cause and control
- Body mass, BMI and type 2 diabetes
- Exothermic changes and reactions
- Endothermic changes and reactions
- Bond breaking and bond making
8. Exchange and transport in animals
- Transporting substances in animals
- Exchange surfaces and transport systems
- Alveoli and gas exchange
- Structure and function of blood
- Structure and function of blood vessels
- The heart and circulatory system
- Cellular respiration, aerobic and anaerobic
- Aerobic and anaerobic respiration compared
- Core practical: rate of respiration
- Heart rate, stroke volume and cardiac output
- Fractions from crude oil and their uses
- How the fractions differ
- Oxides of nitrogen from engines
- Hydrogen compared with petrol as a car fuel
- Fossil fuels from crude oil and natural gas
- Cracking alkanes to make alkenes
- Why cracking is necessary
- Volcanoes and the early atmosphere
- Earth's early atmosphere
- How condensation formed the oceans
- How the oceans reduced carbon dioxide
- Plants and the rise of oxygen
- The test for oxygen
- The greenhouse effect
- Evidence for human activity causing climate change
- Today's atmosphere and the effects of increased greenhouse gases
9. Ecosystems and material cycles
- Levels of organisation in an ecosystem
- Abiotic and biotic factors
- Interdependence in a community
- Parasitism and mutualism
- Core practical: quadrats and belt transects
- Estimating population size from quadrat data
- Positive and negative human interactions with ecosystems: fish farming and non-indigenous species
- Benefits of maintaining biodiversity, conservation and reforestation
- How materials cycle through the abiotic and biotic parts of an ecosystem
- The carbon cycle and the role of decomposers
- The water cycle and the production of potable water
- How nitrates become available to plants: the nitrogen cycle, fertilisers and crop rotation
10. Electricity and circuits
- Structure of the atom
- Circuit diagrams and symbols
- Series and parallel circuits
- Using a voltmeter
- Potential difference and energy
- Energy, charge and potential difference
- Using an ammeter to measure current
- Current as a flow of charge
- The charge, current and time equation
- Current in a closed circuit
- Current at a junction
- Resistance and the variable resistor
- Potential difference, current and resistance (V = IR)
- Resistors in series and in parallel
- Calculations in series circuits
- Designing series circuits for testing and measuring
- Core practical: potential difference, current and resistance
- Current and potential difference for resistors, lamps and diodes
- Resistance of a light-dependent resistor (LDR)
- Resistance of a thermistor
- Investigating resistance in circuit devices
- Heating effect of an electric current
- Energy dissipated by a current doing work against resistance
- Collisions between electrons and ions in the lattice
- Reducing unwanted energy transfer in low resistance wires
- Advantages and disadvantages of the heating effect
- Energy transferred, current, potential difference and time
- Power as energy transferred per second
- Power, energy transferred and time taken
- Power, potential difference and current
- Electrical power: P = IV and P = I²R
- Energy transfers in domestic devices
- Direct and alternating voltage
- Direct current
- Alternating current
- UK mains supply
- Live and neutral wires
- Earth wire, fuses and circuit breakers
- Switches and fuses in the live wire
- Potential differences of the mains wires
- Dangers of a live to earth connection
- Power ratings of domestic appliances
11. Magnetism and the motor effect
- Magnetic poles: attraction and repulsion
- Uses of permanent and temporary magnetic materials
- Permanent and induced magnets
- Magnetic fields around magnets
- Plotting magnetic fields with a compass
- The compass and the Earth's magnetic core
- Magnetic field around a current
- Strength of the field around a wire
- Solenoids and electromagnets
- Force on a current-carrying conductor
- Interacting magnetic fields
- Fleming's left-hand rule
- Force on a conductor in a magnetic field (F = B I l)
12. Electromagnetic induction
- Factors affecting induced potential difference, and how the induced field opposes the change
- Transformers and induction between circuits
- A transformer can change the size of an alternating voltage
- Why electricity is transmitted at high voltage in the national grid
- Step-up and step-down transformers in the national grid
- The transformer power equation
13. Particle model
- Kinetic theory and the states of matter
- The density equation
- Core practical: the densities of solids and liquids
- Density and the states of matter
- Changes of state and conservation of mass
- Heating, internal energy and changes of state
- Specific heat capacity and specific latent heat
- Calculating thermal energy changes
- Calculating energy for a change of state
- Reducing unwanted energy transfer
- Core practical: specific heat capacity of water and melting ice
- Gas pressure and particle motion
- Gas temperature, particle speed and pressure
- Absolute zero
- Kelvin and Celsius scales
14. Forces and matter
- Forces needed to change the shape of an object
- Elastic and inelastic distortion
- Linear elastic distortion and the spring constant
- Work done in stretching a spring
- Linear and non-linear force-extension relationships
- Core practical: force, extension and work done for a spring
- Calculating stored energy and converting units