Biological Molecules
Revision notes for Biological Molecules in OCR Biology A (H020). Every lesson in BrainCake comes with R.E.C.I.P.E. recall steps, a quick check and spaced reviews.
- ElementsThere are about 92 naturally occurring elements.
- BondingThe atoms in organic compounds are held together by strong covalent bonds.
- IonsAtoms are electrically neutral because the number of protons is equal to the number of electrons and the electron and proton have equal and opposite…
- Biological MoleculesThe key biological molecules are carbohydrates, lipids, proteins and nucleic acids.
- PolymersSome biological molecules are very large (macromolecules).
- WaterWater is a polar molecule.
- Hydrogen Bonding and Boiling Point of WaterThe boiling point of water is unusually high for a small molecule of its size.
- Density of WaterWhen water freezes, bonds form between the water molecules and it turns into ice.
- Cohesion, Adhesion and Surface TensionWater molecules are cohesive.
- Specific Heat Capacity of WaterThe specific heat capacity is defined as the energy required to raise the temperature of 1kg of a substance by 1°C.
- Water as a SolventWater is a polar solvent because water molecules have partial charges.
- CarbohydratesCarbohydrates are organic molecules that only contain carbon, hydrogen and oxygen with the general formula Cn(H2O)n.
- GlucoseGlucose is a hexose sugar.
- Other MonosaccharidesMonosaccharides are simple carbohydrates called sugars.
- Condensation ReactionsA condensation reaction is a reaction that joins two molecules together with a covalent bond formed by removing a small molecule such as a water…
- HydrolysisHydrolysis is a reaction in which a covalent bond is broken by the addition of a water molecule.
- DisaccharidesTwo monosaccharides joined together by a covalent bonds is called a disaccharide.
- Test for Reducing SugarsMonosaccharides such as glucose, fructose and galactose can donate electrons to other compounds.
- Test for Non-Reducing SugarsNon-reducing sugars must first be hydrolysed before using the Benedict's test.
- StarchStarch is an energy storage polysaccharide found in plants.
- Test for StarchThe test for starch uses iodine dissolved in potassium iodide solution, which is orange-brown.
- ColorimetryColorimetry can be used as a quantitative method to determine concentrations.
- GlycogenGlycogen is a storage polysaccharide found in animals, fungi and bacteria.
- CelluloseCellulose is a polysaccharide made from beta-glucose.
- BiosensorsBiosensors are biological molecules that can be used to detect the presence of another biological molecule such as glucose or can be used to…
- LipidsLipids are part of a group of large molecules called macromolecules.
- TriglyceridesTriglycerides consist of three fatty acids joined to a glycerol molecule by three ester bonds in a condensation reaction.
- Saturated and Unsaturated Fatty AcidsSome fatty acids contain C=C double bonds and are said to be unsaturated.
- PhospholipidsPhospholipids contain the elements carbon hydrogen, oxygen and phosphorus.
- SterolsSterols are steroid alcohols and include cholesterol and vitamin D sterols.
- Roles of LipidsTriglycerides are stored under the skin in mammals and around vital organs.
- Test for LipidsLipids such as triglycerides are non-polar, so they are insoluble in water but dissolve in organic solvents such as ethanol.
- Lipids and HealthPlant lipids are normally oils because they contain unsaturated fatty acids.
- Amino-acidsAmino acids are monomers that combine to make polymers called polypeptides.
- Thin Layer ChromatographyThin layer chromatography is used to separate components of a mixture.
- PolypeptidesThe amine group of one amino acid can react with the carboxylic acid group of another amino acid in a condensation reaction to join the two amino…
- Protein StructureThe primary structure of a protein or polypeptide is the sequence of amino acids joined together by peptide bonds.
- Hydrolysis of PeptidesThe peptide bonds in dipeptides, polypeptides and proteins can be broken by hydrolysis.
- Globular ProteinsGlobular proteins are water soluble proteins that fold and coil into a tertiary structure in a way that positions hydrophobic R-groups inside the…
- InsulinInsulin is a peptide hormone produced by the pancreas.
- Conjugated ProteinsConjugated proteins contain a non-protein prosthetic group.
- HaemoglobinHaemoglobin is a globular protein containing iron that facilitates the transport of oxygen in red blood cells.
- CatalaseCatalase is an enzyme that catalyses the breakdown of hydrogen peroxide to oxygen and water.
- Fibrous ProteinsProteins perform many different functions in the cell.
- KeratinKeratin is fibrous protein in hair, scales, nails, feathers, horns, claws, hooves, and the outer layer of skin among vertebrates.
- ElastinElastic fibres contains the fibrous protein elastin.
- CollagenCollagen is a fibrous protein that is found in tendons, bones, muscles, skin and blood.
- Test for ProteinsThe Biuret test detects the presence of peptide bonds.
- NucleotidesA nucleotide is an organic compound made of three parts: a pentose sugar - a five carbon sugar such as ribose or deoxyribose An acidic phosphate…
- DNADNA is deoxyribonucleic acid.
- RNARNA is a polynucleotide.
- DNA Extraction1.
- Role of RNASome RNA is involved in regulating transcription and mRNA breakdown. mRNA, rRNA and tRNA are involved in protein synthesis. mRNA transfers genetic…
- DNA ReplicationOrganisms grow and reproduce by cell division.
- Continuous and Dis-continuous ReplicationDNA can only be synthesised in the 5' to 3' direction.
- Replication ErrorsSequences of bases are not always matched exactly.
- The Genetic CodeThe genetic code is the information contained in DNA that allows functional proteins to be synthesised.
- Protein SynthesisThe sequence of nucleotides determines the sequence of amino acids in proteins.
- The role of tRNA, mRNA and rRNAThere are three types of RNA: mRNA, tRNA and ribosomal RNA or rRNA.
- TranscriptionProtein synthesis consists of two stages.
- SplicingSplicing pre-mRNA In eukaryotes, transcription results in pre-mRNA which is a length of RNA with both non-coding and coding sequences.
- TranslationOnce the mRNA leave the nucleus a ribosome attaches to the start codon (triplet of bases) which is always AUG.
- ATPATP is the immediate energy source of a cell.
On the specification
- 2.1.2 Biological molecules
- 2.1.3 Nucleotides and nucleic acids