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Collagen

OCR AS-level BiologyBiological MoleculesLesson 47 of 63

Collagen is a fibrous protein that is found in tendons, bones, muscles, skin and blood. It comprises three-quarters of the skin and a third of all the protein in the human body.

The primary structure is the sequence of amino acids that gives rise to an unbranched polypeptide chain. Every third amino-acid is glycine. The other amino-acids are mostly proline, hydroxyproline and lysine.

Diagram

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Key terms in this lesson

primary structure
The sequence of amino acids in a polypeptide chain, joined by peptide bonds.
tertiary structure
The overall three-dimensional shape of a single polypeptide chain, formed and held by bonds between R groups.
quaternary structure
The structure formed when two or more polypeptide chains, or a polypeptide and a prosthetic group, combine to form a functional protein.
fibrous protein
An insoluble, structural protein made of long, parallel polypeptide chains, such as collagen or keratin.

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