Preparation of Aliphatic Amines
There are two main ways to make aliphatic amines.
1. Halogenoalkane and ammonia. A halogenoalkane is heated with excess ammonia dissolved in ethanol in a sealed tube (ammonia is a gas, so it would escape from an open flask). Ammonia acts as a nucleophile and substitutes for the halogen:
CH3CH2Br + 2NH3 → CH3CH2NH2 + NH4Br
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Key terms in this lesson
- nitrile
- An organic compound containing the carbon-nitrogen triple bond, C triple bond N (the cyano group).
More in Amines, Amides, Amino Acids and Proteins
- Amines
- Basicity of Amines
- Preparation of Phenylamine
- Reactions of Amines with Acids and Acyl Chlorides
- Reactions of Amines with Copper(II) Ions
- Amides
- Condensation Polymers - Polyamides
- Amino Acids
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