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Ionic Bonds

Edexcel AS-level BiologyBiological MoleculesLesson 20 of 25

Some amino acids have R groups that carry an electric charge in the conditions inside cells. An ionic bond in a protein is the attraction between a positively charged R group and a negatively charged R group. It is sometimes called a salt bridge.

• Amino acids such as lysine and arginine have an extra amino group in their R group. At normal pH it gains an H+ and becomes –NH3+.
• Amino acids such as aspartic acid and glutamic acid have an extra carboxyl group in their R group. At normal pH it loses an H+ and becomes –COO−.

–NH3+  ···  −OOC–

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Key terms in this lesson

tertiary structure
The overall three-dimensional shape formed by further folding of a polypeptide chain, held by bonds between R groups.
quaternary structure
The structure formed when two or more polypeptide chains are held together to make one functional protein.

More in Biological Molecules

All 25 lessons in Biological Molecules · All Edexcel AS-level Biology topics