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Protein Structure

Edexcel AS-level BiologyBiological MoleculesLesson 21 of 25

Proteins are described at four levels of structure.

Primary structure is the sequence of amino acids in the polypeptide chain, held together by peptide bonds. It is set by the gene coding for the protein. Changing even one amino acid can change the whole shape of the protein.

Secondary structure is the local coiling or folding of the chain into an α-helix or a β-pleated sheet, held by hydrogen bonds between the C=O and N–H groups of the backbone.

Diagram

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Key terms in this lesson

mutation
A change in the genetic material of a cell, either in the base sequence of DNA or in chromosome structure or number.

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