End-Product Inhibition
End-product inhibition is a way that a cell controls a metabolic pathway: the final product of the pathway inhibits an enzyme that acts near the start of it. It is an example of negative feedback.
Most metabolic pathways are a chain of reactions, each catalysed by its own enzyme:
A → B → C → D (end product)
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Key terms in this lesson
- negative feedback
- A control mechanism in which a change triggers a response that counteracts the change, returning a system towards a set level.
- allosteric site
- A site on an enzyme other than the active site to which a molecule can bind, changing the shape of the active site.
More in Enzymes
- Measuring Rate of Reaction
- Effect of Substrate Concentration
- Effect of Temperature
- Effect of pH
- Effect of Enzyme Concentration
- Reversible and Irreversible Inhibition
- Competitive Inhibition
- Non-competitive Inhibition
All 14 lessons in Enzymes · All Edexcel AS-level Biology topics