Large multicellular organisms need a specialised transport system because simple diffusion is not fast enough to meet their metabolic needs.Oxygen is needed for respiration and carbon dioxide is a waste product and needs to be removed.The larger the organism, the smaller the surface area to volume ratio.More active organisms have higher metabolic demands. Mammals (endotherms) also have to maintain their body temperature.In summary animals have:
- high metabolic demands
- a small surface area to volume ratio
- molecules such as hormones which are made in one place and used in another
- food that needs to be digested and the products transported to every cell
- waste products that need to be removed
- the need to maintain their body temperature