The Krebs Cycle.
The Krebs cycle also occurs in the matrix of the mitochondria. Acetyl coA reacts with 4-carbon oxaloacetate to form 6-carbon citrate and coA is released.
Citrate undergoes decarboxylation and dehydrogenation to form 5-carbon alpha ketogluarate (αKG). Carbon dioxide is released and NAD is reduced.

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Key terms in this lesson
- ATP
- Adenosine triphosphate, the universal energy currency of cells, which releases energy for cellular reactions when hydrolysed to ADP and inorganic phosphate.
- Decarboxylation
- A reaction in which a carboxyl group is removed from a molecule, releasing carbon dioxide.
More in Respiration
- Phosphorylation
- Lysis
- Substrate Level Phosphorylation
- The Link Reaction
- oxidative phosphorylation
- ATP Synthase
- Creatine Phosphate
- Anaerobic Respiration - Plants and Microorganisms.
All 12 lessons in Respiration · All OCR A-level Biology topics