BRAINCAKE

The Krebs Cycle.

OCR A-level BiologyRespirationLesson 7 of 12

The Krebs cycle also occurs in the matrix of the mitochondria. Acetyl coA reacts with 4-carbon oxaloacetate to form 6-carbon citrate and coA is released.

Citrate undergoes decarboxylation and dehydrogenation to form 5-carbon alpha ketogluarate (αKG). Carbon dioxide is released and NAD is reduced.

Diagram

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Key terms in this lesson

ATP
Adenosine triphosphate, the universal energy currency of cells, which releases energy for cellular reactions when hydrolysed to ADP and inorganic phosphate.
Decarboxylation
A reaction in which a carboxyl group is removed from a molecule, releasing carbon dioxide.

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