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Prosthetic Groups

OCR AS-level BiologyEnzymesLesson 19 of 20

Prosthetic groups are non-protein cofactors that are permanently bound to proteins or enzymes and are needed for them to carry out their function.

Metal ions and molecules derived from vitamins can form prosthetic groups.

Diagram

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Key terms in this lesson

disulfide bridge
A covalent bond formed between two cysteine residues that helps stabilise the tertiary or quaternary structure of a protein.
cofactor
A non-protein, inorganic substance needed by an enzyme for it to function correctly.

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