Effect of pH on Enzyme Activity
The tertiary structure of the active site of the enzyme is determined by hydrogen and ionic bonds between -NH2 and -COOH groups and bonding and interactions between the R-groups.
Each enzyme has an optimum pH.
Since the pH is a measure of the hydrogen ion concentration, changes to the H+ concentration may alter the shape of the active site by:
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Key terms in this lesson
- tertiary structure
- The overall three-dimensional shape of a single polypeptide chain, formed and held by bonds between R groups.
- active site
- The region of an enzyme, with a shape complementary to its substrate, where the substrate binds and the reaction is catalysed.