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The Female Gamete

Edexcel AS-level BiologyMeiosis and Sexual ReproductionLesson 18 of 28

In mammals the female gamete released at ovulation is a secondary oocyte. It only completes meiosis II, and becomes a mature ovum, after a sperm enters it. It is often simply called the egg cell.

Diagram

Its structure is adapted for fertilisation and early development:
• Haploid nucleus: contains one set of chromosomes (23 in humans), paused at metaphase II.
• Large cytoplasm containing food reserves such as lipid droplets and proteins, plus mitochondria and ribosomes, to support the early embryo before it implants in the uterus.
• Cortical granules: vesicles just beneath the cell surface membrane containing enzymes. After one sperm enters, they release their contents by exocytosis in the cortical reaction, which hardens the zona pellucida so no further sperm can enter.

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Key terms in this lesson

acrosome reaction
The release of digestive enzymes from a sperm's acrosome when it binds to the zona pellucida, digesting a path towards the egg.

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