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tRNA

AQA AS-level BiologyDNA, Genes and Protein SynthesisLesson 11 of 15

tRNA is a relatively small molecule of around 80 nucleotides that is a single strand folded into a clover leaf shape by hydrogen bonding between bases.

One end of the tRNA molecule extends beyond the other and this acts as an amino-acid binding site. Each tRNA molecule binds a different amino acid with an ester bond.

Diagram

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Key terms in this lesson

hydrogen bond
A weak electrostatic attraction between a slightly positive hydrogen atom on one polar molecule and a slightly negative atom, such as oxygen or nitrogen, on another.
nucleotide
A molecule made of a pentose sugar, a phosphate group and a nitrogen-containing base.
complementary base pairing
The specific pairing of bases by hydrogen bonds, adenine with thymine (or uracil) and guanine with cytosine.
codon
A sequence of three bases on mRNA that codes for a specific amino acid or a stop signal.

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