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Formation of the Brain

Edexcel A-level BiologyMammalian Nervous SystemLesson 29 of 38

The brain and spinal cord develop from a structure in the early embryo called the neural tube.

About three weeks after fertilisation, a strip of ectoderm along the back of the embryo thickens to form the neural plate. The edges of the plate rise up as neural folds, which curl towards each other and fuse, forming a hollow neural tube. This process is called neurulation. If the tube does not close properly, conditions such as spina bifida can result, which is one reason folic acid is recommended in early pregnancy.

By about four weeks, the front end of the tube has swollen into three primary brain vesicles:

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Key terms in this lesson

cerebrum
The largest part of the brain, divided into two hemispheres, responsible for conscious thought, sensation and voluntary movement.

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