Sex-Linked Diseases
Sex-linked diseases are caused by faulty alleles of genes on the sex chromosomes. Most are X-linked recessive. Well-known examples include haemophilia, red-green colour blindness and Duchenne muscular dystrophy.
Because males have only one X chromosome, a male with one recessive allele (XaY) is affected. A female needs two recessive alleles (XaXa) to be affected; a female with one (XAXa) is an unaffected carrier.
Typical features of X-linked recessive inheritance:
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Key terms in this lesson
- carrier
- A heterozygous individual who carries a recessive allele for a condition without showing it themselves.
More in Genetic Information
- Gene Linkage
- Identifying Linked Genes
- Chromosome Mapping
- Sex-Linkage
- Pedigree Diagrams
- The Albino Trait
- Red-Green Colour Blindness
- Haemophilia
All 30 lessons in Genetic Information · All Edexcel A-level Biology topics