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The Role of Ca2+ and ATP in Muscle Contraction

    Calcium ions have a dual role in muscle contraction.
  • They bind to troponin to move tropomyosin and expose the myosin binding sites
  • They activate the ATPase activity of the myosin head
    ATP has a dual role in muscle contraction.
  • It provides the energy for the active transport of Calcium ions into the SR
  • The binding of ATP to the myosin head detaches it from the actin filament and the hydrolysis of ATP returns the myosin head to its original position.

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Specification: AQA Biology (7402), A-level, 3.6.3 Skeletal muscles are stimulated to contract by nerves and act as. Topic: Muscles.

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