Bulk transport is a form of active transport and requires energy.Molecules too large to pass through channel or carrier proteins such as such as enzymes and peptide hormones can be transported into and out of the cell in vesicles.Endocytosis involves transport into the cells from the external environment.Phagocytosis is the transport of large molecules and pinocytosis is transport of fluids.The membrane invaginates and pinches off to form a vesicle that encloses the molecule to be taken in.The vesicle then moves into the cytoplasm.Vesicles containing bacteria fuse with lysosomes and the lysozyme digests and destroys the bacteria.Exocytosis involves the reverse process.Vesicles containing the molecules to be exported fuse with the membrane and release the contents outside the cell.Endocytosis and exocytosis use energy in the form of ATP.