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Metaphase 1

Homologous pairs of chromosomes assemble along the metaphase plate. The random orientation of the homologous pairs leads to 223 different combinations in humans.The maternal and paternal chromosomes can end up facing either pole. This is called independent assortment and leads to genetic variation.

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Specification: OCR Biology A (H020), AS-level, 2.1.6 Cell division, cell diversity and cellular organisation. Topic: Cell Division.

Key terms in this lesson

metaphase plate
The imaginary plane at the equator of the spindle where chromosomes align during metaphase of mitosis or meiosis.

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