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DNA Replication

Edexcel AS-level BiologyDNA, Genes and Protein SynthesisLesson 7 of 20

DNA is copied before a cell divides, during interphase, so that each daughter cell receives an identical copy. Replication is semi-conservative.

The steps are:

1. The enzyme DNA helicase breaks the hydrogen bonds between complementary bases, so the double helix unwinds and the two strands separate.
2. Each original strand acts as a template.
3. Free, activated DNA nucleotides in the nucleus are attracted to their complementary exposed bases (A to T, C to G) and are held by hydrogen bonds.

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Key terms in this lesson

antiparallel
Describes two strands of a double helix running in opposite directions, one 5' to 3' and the other 3' to 5'.

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