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Antibody Function

Antibodies work in various ways to stop pathogens from causing damage to cells.Agglutination.Antibodies bind to antigens on pathogens and cause the cells to clump together in one place so they are less spread out within the body.This makes it easier for phagocytes to locate and engulf the bacteria.Opsonisation.Antibodies coat the pathogen so that the pathogen is easily identified by phagocytes.Neutralisation.The binding of an antibody to a virus or toxin neutralises the virus or toxin by making then unable to bind to their targets.Viruses will be unable to gain entry into cells and toxins will be unable to interfere with metabolic processes.

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Specification: AQA Biology (7401), AS-level, 3.2.4 Cell recognition and the immune system. Topic: Cell Recognition and the Immune System.

Key terms in this lesson

pathogen
A microorganism, such as a virus, bacterium, fungus or protoctist, that causes disease.
antigen
A protein or glycoprotein, usually on a cell surface, that is recognised as foreign by the immune system and triggers an immune response.
antibody
A Y-shaped protein, made of four polypeptide chains with variable regions complementary to a specific antigen, produced by B plasma cells.

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