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Antibody Structure

AQA AS-level BiologyCell Recognition and the Immune SystemLesson 12 of 30

Antibodies are small, soluble Y-shaped proteins made up four polypeptide chains. They are called immunoglobulins (Ig) and there are various types. The most common is IgG.

There are a pair of shorter polypeptides known as light chains and a pair of longer polypeptide chains known as heavy chains.

The chains are linked together by disulfide bridges.

Diagram

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Key terms in this lesson

disulfide bridge
A strong covalent bond formed between two sulfhydryl (-SH) groups of cysteine residues in a polypeptide.
pathogen
A microorganism, such as a virus, bacterium, fungus or protoctist, that causes disease.
antigen
A protein or glycoprotein, usually on a cell surface, that is recognised as foreign by the immune system and triggers an immune response.
B-lymphocyte
A type of white blood cell, matured in the bone marrow, responsible for the humoral immune response and antibody production.

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