Monoclonal antibodies are used in home pregnancy test kits.Early on in pregnancy the placenta produces the hormone hCG (human chorionic gonadotropin) which can be found in the mother's urine.Mobile monoclonal antibodies are linked to coloured particles. Immobile monoclonal antibodies on a test strip will bind to the mobile antibodies if they are bound to hCG.If hCG is present in the urine it binds to the mobile monoclonal antibodies. The hCG-antibody-colour complex moves along the strip until it is trapped by the immobilised antibodies creating a coloured line.
Pregnancy Testing
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Specification: AQA Biology (7401), AS-level, 3.2.4 Cell recognition and the immune system. Topic: Cell Recognition and the Immune System.
Key terms in this lesson
- antibody
- A Y-shaped protein, made of four polypeptide chains with variable regions complementary to a specific antigen, produced by B plasma cells.
- monoclonal antibody
- An antibody produced from a single clone of B cells, identical in structure and specific to one antigen.
More in Cell Recognition and the Immune System
- Antibody Function
- Monoclonal Antibodies
- Drug Delivery and Therapy
- Medical Diagnosis
- Ethics
- Producing Monoclonal Antibodies
- Active, Passive, Natural and Artificial Immunity
- Vaccination
All 30 lessons in Cell Recognition and the Immune System · All AQA AS-level Biology topics