Skip to content

Collagen

Collagen is a fibrous protein that is found in tendons, bones, muscles, skin and blood vessel walls.It comprises three-quarters of the skin and a third of all the protein in the human body.The primary structure is the sequence of amino acids that gives rise to an unbranched polypeptide chain.Every third amino-acid is glycine. The other amino-acids are mostly proline, hydroxyproline and lysine.The secondary structure consists of a tightly wound molecule.The molecule has a tertiary structure; it is twisted into a second helix.The quaternary structure consists of three helices tightly wound round each other and cross-linked by lysine residues.Every third amino-acid is glycine to ensure the individual chains can get close to each other to be tightly wound.The ends are staggered to ensure that a line of weakness does not run through the molecule.

Read the text

Read the text and highlight anything you think is important. When you go on, the text is hidden and you answer from memory.

Specification: AQA Biology (7401), AS-level, 3.1.4.1 General properties of proteins. Topic: Biological Molecules.

Key terms in this lesson

primary structure
The sequence of amino acids in a polypeptide chain.
secondary structure
The coiling or folding of a polypeptide chain, such as into an alpha-helix or beta-pleated sheet, caused by hydrogen bonding between peptide bonds.
tertiary structure
The further coiling and folding of a polypeptide into a specific three-dimensional shape, held by ionic bonds, hydrogen bonds and disulfide bridges between R-groups.
quaternary structure
The structure formed when two or more polypeptide chains, and sometimes a non-protein prosthetic group, are held together to form a functional protein.
fibrous protein
A protein made of long parallel polypeptide chains with cross links, usually insoluble and with a structural role.

More in Biological Molecules

All 29 lessons in Biological Molecules · All AQA AS-level Biology topics