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Peptide Bond Formation

AQA AS-level BiologyBiological MoleculesLesson 22 of 29

Amino acids join together by condensation reactions. The -OH from the carboxyl group of one amino acid combines with an -H from the amino group of another, and a molecule of water is removed.

The covalent bond that forms between the carbon of the carboxyl group and the nitrogen of the amino group is called a peptide bond, -CONH-. Two amino acids joined in this way form a dipeptide.

Diagram

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Key terms in this lesson

condensation reaction
A reaction that joins two molecules together with a covalent bond, with the elimination of a water molecule.
hydrolysis
The breaking of a covalent bond within a molecule using a water molecule.

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