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Generator Potential

Normally, the sensory neurone is at its resting potential. The axon membrane is negative on the inside. When pressure is applied to the Pacinian corpuscle, the membrane of the neurone stretches and a stretch-mediated sodium ion channel changes shape and widens to allow the diffusion of sodium ions into the neurone.The potential of the neurone changes and it becomes depolarised resulting in a generator potential which then creates an action potential (electrical impulse) that passes along the neurone.

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Specification: OCR Biology A (H420), A-level, 5.1.3 Neuronal communication. Topic: Neuronal Communication.

Key terms in this lesson

Sarcomere
The contractile unit of a myofibril, delineated by two Z-lines, containing overlapping actin and myosin filaments.
Actin
A thin protein filament in a myofibril that, together with myosin, slides during muscle contraction.
Myosin
A thick protein filament in a myofibril with globular heads that bind to actin and pull it during muscle contraction.

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