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Chromosome Mutations

OCR A-level BiologyGenetics and VariationLesson 7 of 36

If the number of chromosomes in a cell changes as in Down's syndrome, or the mutation affects the whole chromosome, this is known as a chromosome mutation. Normally, chromosome mutations occur during meiosis and whilst they may be silent, they often lead to problems in development.

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Key terms in this lesson

Mutation
A change in the base sequence of DNA.

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