BRAINCAKEDNA Profiling
Strands of DNA are cut into small fragment using restriction endonucleases. There are thousands of different restriction enzyme each cutting DNA at a specific sequence or recognition site. A combination of restriction enzymes leaves the micro and mini-satellite regions intact.
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Key terms in this lesson
- Gel electrophoresis
- A technique that separates fragments of DNA, or other charged molecules, according to size by passing an electric current through a gel, with smaller fragments moving further.
- Southern blotting
- A technique for transferring separated DNA fragments from an electrophoresis gel onto a nylon or nitrocellulose membrane so that they can be probed.
More in Genetic Engineering and Biotechnology
- Non-coding DNA
- Gel Electrophoresis
- The Polymerase Chain Reaction
- DNA Sequencing
- Automated Sequencing
- Pathogens, DNA Barcoding
- Genomics and Proteomics
- Recombinant DNA
All 17 lessons in Genetic Engineering and Biotechnology · All OCR A-level Biology topics