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The Calvin Cycle

Edexcel A-level BiologyPhotosynthesisLesson 12 of 20

The Calvin cycle is the series of enzyme-controlled reactions in the stroma that fixes carbon dioxide into carbohydrate.

Diagram

1. Carbon fixation: CO2 combines with ribulose bisphosphate (RuBP), a 5-carbon compound, catalysed by RUBISCO. The unstable 6-carbon product immediately splits into two molecules of glycerate 3-phosphate (GP), a 3-carbon compound.
2. Reduction: GP is reduced to glyceraldehyde 3-phosphate (GALP), a 3-carbon sugar phosphate (triose phosphate), using hydrogen from reduced NADP and energy from ATP. The NADP and ADP return to the thylakoids to be reused.

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Key terms in this lesson

nadp
A coenzyme that acts as a hydrogen acceptor in the light-dependent reactions of photosynthesis, becoming reduced NADP when it accepts hydrogen.
rubisco
The enzyme that catalyses the fixation of carbon dioxide by combining it with RuBP in the Calvin cycle, and can also catalyse a competing reaction with oxygen (photorespiration).

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