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Hyperpolarisation

Edexcel A-level BiologyMammalian Nervous SystemLesson 11 of 38

Hyperpolarisation is the brief period after repolarisation when the membrane potential becomes more negative than the resting potential, falling to about −80 mV instead of −70 mV.

It happens because the voltage-gated potassium ion channels are slow to close. During repolarisation K+ diffuses out of the axon. When the potential gets back to −70 mV, many K+ channels are still open, so K+ keeps leaving and the inside becomes more negative than at rest. This is sometimes called the undershoot.

The resting potential is then restored in two ways:

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Key terms in this lesson

refractory period
The short time after an action potential during which a new action potential cannot be generated, or only by a stronger than normal stimulus.

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