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Action Potential

Edexcel A-level BiologyMammalian Nervous SystemLesson 8 of 38

An action potential is a brief reversal of the potential difference across the membrane of a neurone, from about −70 mV (inside negative) to about +40 mV (inside positive). It lasts about 2 to 3 ms and is caused by the opening and closing of voltage-gated ion channels.

The sequence of events is shown on a graph of membrane potential against time:

Diagram

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