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Using Embryonic Stem Cells

Edexcel A-level BiologyGene ExpressionLesson 37 of 39

Embryonic stem cells are taken from the inner cell mass of a blastocyst, an early embryo about 5 days after fertilisation. At this stage the embryo is a hollow ball of only around 100 cells.

Properties
• They are pluripotent, so they can become any cell type of the body.
• They can divide indefinitely in culture, giving a large supply of cells.

Sources
• Spare embryos from IVF treatment, donated with the parents' consent.
• Embryos made by therapeutic cloning, which are genetically matched to a patient.

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Key terms in this lesson

blastocyst
An early embryo, formed about five days after fertilisation, consisting of a hollow ball of cells with an outer trophoblast layer and an inner cell mass.
pluripotent
Describes a cell able to differentiate into any type of body cell, but not extra-embryonic tissues such as the placenta.
teratoma
A tumour of disorganised tissues that can form if undifferentiated stem cells are transplanted into the body.

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