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Diseases that Could Be Treated

Edexcel A-level BiologyGene ExpressionLesson 31 of 39

Stem cell therapy is most promising for diseases caused by the loss or damage of a particular cell type that the body cannot replace. If that cell type can be grown from stem cells and put back in the right place, normal function could be restored.

Examples being researched include:
• Type 1 diabetes: loss of insulin-secreting beta cells in the pancreas.
• Parkinson's disease: death of neurones in the brain that release the neurotransmitter dopamine, causing tremor and slow movement.
• Spinal cord injury and multiple sclerosis: damage to neurones or to the myelin around them.

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Key terms in this lesson

leukaemia
A cancer of blood-forming tissue, usually the bone marrow, causing production of abnormal white blood cells.
sickle cell disease
An inherited blood disorder in which a mutant allele of the haemoglobin gene causes red blood cells to become rigid and sickle-shaped, impairing oxygen transport.

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