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Phytochrome as a Transcription Factor

Edexcel A-level BiologyChemical ControlLesson 30 of 30

Phytochrome causes long-lasting changes in the plant, such as greening, by changing which genes are expressed.

Pr is found in the cytoplasm. When it absorbs red light and is converted to Pfr, the molecule changes shape. This exposes a signal that lets Pfr move through the nuclear pores into the nucleus.

In the nucleus, Pfr binds to proteins called phytochrome-interacting factors (PIFs). PIFs are transcription factors: they bind to the promoter regions of target genes and control whether RNA polymerase can transcribe them. In the dark, PIFs keep the seedling etiolated. When Pfr binds to them, the PIFs are tagged for breakdown, so the genes they were controlling are switched on or off.

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Key terms in this lesson

phytochrome
A blue-green plant pigment existing in two interconvertible forms sensitive to red and far-red light, controlling responses such as flowering and germination.

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