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Codominance Genetic Crosses

Genetic crosses involving codominant alleles are set out in the same way as other monohybrid crosses, but each genotype gives a different phenotype, so the phenotypic ratio matches the genotypic ratio.Take coat colour in shorthorn cattle: CRCR red, CWCW white, CRCW roan.Cross 1: red × white
Parents: CRCR × CWCW
Gametes: all CR and all CW
Offspring: all CRCW, so all roan.Cross 2: roan × roan
Parents: CRCW × CRCW
Gametes: CR or CW from each parent
CRCW
CRCRCRCRCW
CWCRCWCWCW

Genotypic ratio 1 CRCR : 2 CRCW : 1 CWCW
Phenotypic ratio 1 red : 2 roan : 1 whiteCross 3: roan × white
CRCW × CWCW gives 1 roan : 1 white.Worked example
Two roan cattle produce 80 calves over several years. How many would you expect to be roan?
expected roan = 2/4 × 80 = 40
Remember that ratios are probabilities. Real numbers of offspring rarely match them exactly, because fertilisation is random.

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