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Autosomal Linkage and Recombinant Offspring

AQA A-level BiologyGenetics and VariationLesson 41 of 41

An autosome is any chromosome that is not a sex chromosome. Two genes are autosomally linked when their loci are on the same autosome.

Linked genes do not assort independently in meiosis. Their alleles tend to be inherited together, because they are carried on the same chromosome into the same gamete. As a result, a dihybrid cross involving linked genes does not give the expected 9 : 3 : 3 : 1 (or 1 : 1 : 1 : 1 in a test cross). Instead, most offspring have the same combinations of alleles as the parents.

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Key terms in this lesson

allele
One of two or more alternative versions of a gene, occupying the same locus on homologous chromosomes.
heterozygous
Having two different alleles of a particular gene.

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