BRAINCAKEChromosome Mutations
If the number of chromosomes in a cell changes as in Down's syndrome, or the mutation affects the whole chromosome, this is known as a chromosome mutation. Normally, chromosome mutations occur during meiosis and whilst they may be silent, they often lead to problems in development.
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Key terms in this lesson
- mutation
- A random change in the base sequence of DNA (a gene mutation) or in the structure or number of chromosomes (a chromosome mutation).
More in Genetics and Variation
- Effects of Mutations
- Change in Protein Function
- Sickle-cell Anaemia
- Causes of mutations
- Gene Regulation
- Controlling Transcription
- Lac Operon
- Cyclic AMP
All 36 lessons in Genetics and Variation · All AQA A-level Biology topics