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Change in Protein Function

  • Amorph effect - the mutation results in a loss of function of the protein.
  • Hypomorph effect - the mutation results in a reduction of function of the protein.
  • Hypermorph - the mutation enhances the function of the protein.

Non-sense mutations lead to a stop codon replacing the codon for an amino-acid.

Mis-sense mutations lead to an amino-acid being replaced. Conservative mutations replace the amino-acid with one with similar properties. Non-conservative mutations replace the amino-acid with one with different properties.

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