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Reactions of Acyl Chlorides with Water, Alcohols, Ammonia and Amines

Edexcel A-level ChemistryCarboxylic Acids and DerivativesLesson 9 of 12

Acyl chlorides react rapidly at room temperature with nucleophiles that have a lone pair on an oxygen or nitrogen atom. In every case HCl is eliminated.

1. Water gives a carboxylic acid. The reaction is vigorous and gives steamy fumes of HCl.

CH3COCl + H2O → CH3COOH + HCl

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Key terms in this lesson

amide
An organic compound containing the -CONH2 (or N-substituted) functional group, derived from a carboxylic acid.

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