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Acylation of Water, Alcohols, Ammonia and Amines

AQA A-level ChemistryCarboxylic Acids and DerivativesLesson 15 of 16

Acylation is the addition of an acyl group, RCO, to a molecule. Acyl chlorides and acid anhydrides acylate four types of nucleophile. Using ethanoyl chloride:

Water gives a carboxylic acid:

CH3COCl + H2O → CH3COOH + HCl

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