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Cholesterol

Cholesterol is a hydrophobic molecule that occurs within the membrane.It adds strength to the membrane, regulates the fluidity of the membrane and prevents the leakage of water and ions across the membrane.The cholesterol molecules pull the fatty acid chains together and limit their movement in the phospholipid bilayer.This makes the membrane less fluid, protects against disruption of the membrane at high temperatures and limits the lateral movement of molecules within the membrane.

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Specification: OCR Biology A (H020), AS-level, 2.1.5 Biological membranes. Topic: Plasma Membrane.

Key terms in this lesson

phospholipid bilayer
Two layers of phospholipid molecules arranged with hydrophilic heads facing outwards and hydrophobic tails facing inwards, forming the basic structure of cell membranes.

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