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RNA Viruses

Edexcel AS-level BiologyProkaryotic CellsLesson 13 of 31

RNA viruses have a genome made of RNA rather than DNA. The RNA may be single-stranded (ssRNA) or, less often, double-stranded (dsRNA).

Examples of RNA viruses include:
• influenza virus (flu)
• measles virus
• rhinoviruses (most common colds)
• poliovirus
• SARS-CoV-2 (COVID-19)
• Ebola virus
• tobacco mosaic virus (a plant virus)

Single-stranded RNA viruses are divided into two groups by the sense of their genome:
• positive-sense (+ssRNA): the genome has the same base sequence as mRNA, so it can be translated directly by host ribosomes (e.g. poliovirus, SARS-CoV-2).

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Key terms in this lesson

retrovirus
An RNA virus that copies its genome into DNA using reverse transcriptase before inserting it into the host cell's chromosome.

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