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Virus Life Cycle

Edexcel AS-level BiologyProkaryotic CellsLesson 16 of 31

Although viruses differ in detail, their replication inside a host cell follows the same general sequence of stages:

1. Attachment: viral proteins bind to specific receptors on the host cell.
2. Entry (penetration): the viral nucleic acid enters the cell, by injection, endocytosis or membrane fusion.
3. Replication and synthesis: the viral genome is copied many times, and viral genes are transcribed and translated by the host to make capsid proteins and enzymes.
4. Assembly: new nucleic acid and capsid proteins come together to form new virus particles.
5. Release: new virions leave the cell, either by bursting it (lysis) or by budding through the membrane, which gives enveloped viruses their envelope.

Diagram

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Key terms in this lesson

prophage
Bacteriophage DNA inserted into the host bacterial chromosome and replicated along with it during the lysogenic pathway.

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