Metaphase
Metaphase: By metaphase, chromosomes have reached the metaphase plate (or equator) in the middle of the cell.
They are attached to the spindles by their centromeres.

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Key terms in this lesson
- ATP
- Adenosine triphosphate, a nucleotide that acts as the immediate energy source in cells, releasing energy when hydrolysed to ADP and phosphate.
- centromere
- The region of a chromosome where the two sister chromatids are held together and where spindle fibres attach.
- spindle fibres
- Protein fibres that extend across a dividing cell and attach to the centromeres of chromosomes, pulling them apart.
More in The Cell Cycle
- The Cell Cycle
- Mitosis
- Prophase
- Anaphase
- Telophase
- Cytokinesis
- The Importance of Mitosis
- Cancer and the Control of Mitosis
All 12 lessons in The Cell Cycle · All AQA AS-level Biology topics