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Enzyme Structure

AQA AS-level BiologyEnzymesLesson 2 of 17

Enzymes have a specific 3D shape (tertiary structure) as a result of their amino-acid sequence.

A region of the enzyme, known as the active site, creates a small depression in the enzyme that is responsible for the enzyme's catalytic activity.

The substrate or substrates fit into the active site to form an enzyme-substrate complex because the shape of the active site is complementary to the shape of the substrate.

Diagram

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Key terms in this lesson

ionic bond
A strong bond formed by the electrostatic attraction between oppositely charged ions.
hydrogen bond
A weak electrostatic attraction between a slightly positive hydrogen atom on one polar molecule and a slightly negative atom, such as oxygen or nitrogen, on another.
tertiary structure
The further coiling and folding of a polypeptide into a specific three-dimensional shape, held by ionic bonds, hydrogen bonds and disulfide bridges between R-groups.

More in Enzymes

All 17 lessons in Enzymes · All AQA AS-level Biology topics