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Multiple Alleles

OCR A-level BiologyGenetics and VariationLesson 39 of 41

Multiple alleles means that a gene has more than two alleles in the population. However, each diploid individual can only carry two of them, one on each chromosome of a homologous pair, because it has only two copies of the gene locus.

Multiple alleles arise because different mutations of the same gene produce several versions of the gene. They often show a hierarchy of dominance, and some pairs may be codominant.

Example: the ABO blood group gene. The gene I codes for an enzyme that adds sugars to an antigen on the surface of red blood cells. There are three alleles:

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Key terms in this lesson

codominance
A type of inheritance in which two different alleles of a gene are both expressed in the phenotype of a heterozygote, rather than one masking the other.

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