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Multiple Allele Crosses - ABO Blood Groups

OCR A-level BiologyGenetics and VariationLesson 40 of 41

ABO blood groups are controlled by one gene with three alleles: IA and IB are codominant, and both are dominant to IO. The genotypes and phenotypes are:

• Group A: IAIA or IAIO
• Group B: IBIB or IBIO
• Group AB: IAIB
• Group O: IOIO

Worked example: a heterozygous group A father and a heterozygous group B mother have children.

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Key terms in this lesson

codominance
A type of inheritance in which two different alleles of a gene are both expressed in the phenotype of a heterozygote, rather than one masking the other.

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