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The Effector Stage

Edexcel A-level BiologyResponse to InfectionLesson 9 of 20

In the specific immune response, effector cells are the cells that actually carry out the attack on the pathogen. In the humoral response the effector cells are plasma cells, and the effector stage is when they secrete large quantities of antibodies.

Plasma cells are specialised for making and secreting protein. They have:
• a large amount of rough endoplasmic reticulum, where ribosomes synthesise the antibody polypeptides
• a large Golgi apparatus, which modifies the antibodies (adding carbohydrate to form glycoproteins) and packages them into vesicles
• many mitochondria to supply ATP for protein synthesis and secretion.

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Key terms in this lesson

golgi apparatus
An organelle made of stacked, flattened membranous sacs that modifies, packages and sorts proteins, often adding carbohydrate to form glycoproteins.

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