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Determination of Cell Type

Edexcel A-level BiologyGene ExpressionLesson 20 of 39

Determination is the process by which a cell becomes committed to developing into a particular type of cell. It happens before the cell shows any visible signs of specialisation. Differentiation comes afterwards, when the cell develops the structures and proteins of its final cell type.

A determined cell may look exactly like the cells around it, but its fate is already fixed. If a determined cell is moved to a different part of the embryo, it still develops into the cell type it was committed to, not the type normally found in its new position.

What determines a cell's fate?

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Key terms in this lesson

transcription factor
A protein that binds to DNA near a gene and helps or prevents RNA polymerase binding to the promoter, switching the gene on or off.

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