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Gene Mutations

AQA AS-level BiologyGenetic DiversityLesson 3 of 19

A change in the sequence of DNA is called a gene mutation.

This change will be copied to an mRNA strand and translated into a protein.

This could lead to a different sequence of amino acids and this may affect the secondary, tertiary and quaternary structures of the protein leading to a protein that functions differently or does not function at all.

Diagram

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Key terms in this lesson

nucleotide
A molecule made of a pentose sugar, a phosphate group and a nitrogen-containing base.
gene
A length of DNA that codes for a polypeptide or a functional RNA molecule, at a specific locus on a chromosome.
codon
A sequence of three bases on mRNA that codes for a specific amino acid or a stop signal.
mutation
A random change in the amount, arrangement or base sequence of the DNA of an organism.

More in Genetic Diversity

All 19 lessons in Genetic Diversity · All AQA AS-level Biology topics