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Deletion of Bases

AQA AS-level BiologyGenetic DiversityLesson 5 of 19

Base deletions almost always lead to loss of function of the protein as they involve a shift of the reading frame to the left

They are therefore called frameshift mutations.

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Key terms in this lesson

nucleotide
A molecule made of a pentose sugar, a phosphate group and a nitrogen-containing base.
mutation
A random change in the amount, arrangement or base sequence of the DNA of an organism.

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